1. Uber CEO Dara Khosrowshahi explains how AI agents and $10 billion in autonomous vehicle bets reshape travel, hotels, and driver roles.

2. iRobot founder Colin Angle outlines Familiar Machines’ EQ-first companion robots that combat loneliness through on-edge emotional AI by 2027.

3. Lean Startup pioneer Eric Ries argues best practices erode trust and innovation, offering a three-phase plan to safeguard entrepreneurship.

4. Atlassian CEO Mike Cannon-Brookes demonstrates why context trumps compute in building AI-native teams via teamwork graphs and productivity metrics.

5. Airbnb CEO Brian Chesky introduces AI founder mode with elite Project Hawaii teams that slash management layers and deliver revenue lifts.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

Dara Khosrowshahi on replacing Uber drivers — and himself — with AI

Decoder with Nilay Patel

Listen on: Spotify | Apple Podcasts | YouTube | Podlink

Topics: AI | Leadership | Product | Robotics | Technology

Uber CEO Dara Khosrowshahi discusses expanding into travel, hotels, and shopping whilst navigating autonomy, AI-driven customer service, and the future of driver employment.

● Uber is leveraging its 100 million annual airport riders to build travel and hotel booking features, partnering with Expedia to create a unified travel experience within the app.

● The company is replacing rigid customer service policies with AI agents trained on outcomes rather than rules, allowing for contextual decision-making at scale.

● Uber is committing $10 billion to autonomous vehicles through partnerships with Rivian, Lucid, Nuro, and others, betting multiple providers will succeed rather than one dominant player.

“Everything is theory until you get punched in the face.” - Dara Khosrowshahi

Inside Colin Angle’s bid to build companion robots with Familiar Machines & Magic

The Robot Report Podcast

Listen on: Spotify | Apple Podcasts | YouTube | Podlink

Topics: AI | Hardware | Robotics | Startups

iRobot founder Colin Angle unveils Familiar Machines’ companion robot targeting emotional AI in homes.

● Angle targets $2.35T consumer physical AI market focussed on human connection over industrial tasks.

● Familiar uses EQ-first AI for expression via motion and sounds, prioritising routines to combat loneliness.

● Robot processes all data on-edge for privacy, plans 2027 launch at pet-equivalent ownership cost.

“Selling a million familiars has more economic value than all of the Roombas ever sold.” - Colin Angle

So-called “best practices” for organisational management will destroy your company – with Eric Ries

Product Mastery Now for Product Managers, Leaders, and Innovators

Listen on: Spotify | Apple Podcasts | YouTube | Podlink

Topics: Leadership | Product | Startups

Lean Startup pioneer Eric Ries argues so-called best practices destroy companies by eroding trust and innovation.

● Traditional forecasting and controls clash with entrepreneurship’s uncertainty, blocking innovation.

● Implement three-phase change: exceptions for experiments, then directives, finally deep systems like budgeting.

● Treat trustworthiness as a core asset; product leaders must protect it against short-term pressures.

“so-called best practices we’ve all been taught about how organizations should be built, managed, and governed are value destroying.” - Eric Ries

How to Build an AI Native Team with Mike Cannon-Brookes

The AI Daily Brief: Artificial Intelligence News and Analysis

Listen on: Spotify | Apple Podcasts | Podlink

Topics: AI | Leadership | Productivity | Technology

Atlassian CEO Mike Cannon-Brookes explains why context, not compute, drives enterprise AI adoption and how organisations transition from AI novices to AI-native teams.

● Intelligence multiplied by context accelerates business outcomes; the teamwork graph now indexes code semantics, organisational skills, and physical assets across 150 billion connections.

● Leading organisations prioritise throughput, flow, and output quality over token consumption, using tools like DX to measure engineering productivity rather than raw AI usage metrics.

● AI moves beyond chat into natural product experiences across Jira, Confluence, and Dia, meeting users where they work without requiring prompt engineering expertise.

“The best organisations are talking about throughput and flow and output and quality of output, not quantity of output.” - Mike Cannon-Brookes

Brian Chesky - AI Founder Mode

Invest Like the Best with Patrick O’Shaughnessy

Listen on: Spotify | Apple Podcasts | YouTube | Podlink

Topics: AI | Leadership | Startups | Product

Airbnb CEO Brian Chesky outlines AI founder mode for leading in the AI era.

● Project Hawaii deploys 10-12 person elite teams to solve one problem at a time, delivering 600 basis points in revenue lift through crawl-walk-run-fly stages.

● AI founder mode eliminates pure people managers, requiring hybrid leaders who code or directly touch customer-facing work while slashing management layers to four.

● 11-star exercise escalates from personalised wine at check-in to Beatles-style parades and space flights, revealing scalable six-star delights for product-market fit.

“AI founder mode is going to be even more intense than founder mode.” - Brian Chesky

1. AppLovin CEO Adam Foroughi explains scaling to a $160B market cap through lean teams generating $10M EBITDA per head via AI-driven efficiency and aggressive execution.

2. Eric Friedman, senior principal data scientist at Atlassian, shows how gut intuition and accuracy over precision dodge costly data blunders in business analytics.

3. Tom Wigg and Stephen Byrd argue AI capabilities accelerate exponentially, promising massive revenue surges for hyperscalers by 2026 as agentic workflows dominate.

4. Founders from Factory AI, LiveKit, and Hebbia analyse Cursor’s $60B deal alongside DeepSeek V4’s cost edge, as LLM commoditisation erodes AI moats entirely.

5. IBM Infrastructure COO Barry Baker demonstrates why mainframes process 25 billion daily transactions with unmatched reliability, turbocharged by AI for fraud detection in milliseconds.

Pick an episode below, press play, lace up and get moving.

Podcast Recommendations

1. Applovin: $160BN Market Cap, $5.48BN Revenue, $10M EBITDA Per Head

The Twenty Minute VC

Listen on: Spotify | Apple Podcasts | Podlink (1 h 21 m)

Topics: AI | Leadership | Startups | Strategy | Venture Capital

AppLovin CEO Adam Foroughi explains scaling to $160B market cap with $10M EBITDA per head through lean teams and AI-driven efficiency.

● Founders chase winning over fear of loss; money motivates short-term but personal growth drives long-term success.

● Cut bloated processes and staff 40-50% to rebuild AI-native organisations of doers who adopt tools rapidly.

● Aggression outperforms kindness in business; sugarcoating wastes time and slows execution.

“the founder mentality has got to be chase winning.” - Adam Foroughi

2. Avoiding Major Oopsies: Twyman’s Law, Intuition, and Valuing Accuracy Over Precision

The Analytics Power Hour

Listen on: Spotify | Apple Podcasts | Podlink (1 h 4 m)

Topics: Data | Leadership | Product | Strategy

Eric Friedman, senior principal data scientist at Atlassian, explains how trusting your intuition and prioritising accuracy over precision prevents costly data mistakes.

● When data looks suspiciously good, trust your gut. Intuition serves as a final line of defence against undetected bugs that rigorous checks miss.

● Accuracy and precision differ fundamentally in business contexts. An approximate answer to the right question outweighs an exact answer to the wrong one.

● Document assumptions upfront and involve stakeholders in validation checkpoints. Peer review and cross-checking calculations prevent misaligned measurements across teams.

“Our intuition, that’s part of our expert opinion. We should sometimes just go with it.” - Eric Friedman

3. AI’s Next Big Leap

Thoughts on the Market

Listen on: Spotify | Apple Podcasts | Podlink (10 m)

Topics: AI | Strategy | Technology | Venture Capital

Tom Wigg and Stephen Byrd argue that AI capability improvements are accelerating exponentially rather than linearly, with major revenue inflection expected in 2026.

● AI capabilities are improving nonlinearly—roughly doubling when training compute rises 10x—which will unlock underappreciated, low‑cost AI use cases across most industries and force investors to distinguish between business models that are disrupted, enabled, or largely immune.

● Stephen Byrd makes a bullish case that, despite current concerns about hyperscalers’ capex and stock performance, token economics are highly attractive for both providers and adopters, creating strong pricing power for those controlling scarce compute and supporting continued infrastructure investment.

● As enterprises move from simple queries to agentic AI across many knowledge workflows, token usage and compute demand should surge, with early fast adopters already seeing massive productivity gains and pointing to a likely revenue inflection for hyperscalers around 2026 as broader adoption catches up.

“We’re living in almost two worlds where the fast adopters will show what’s possible.” - Stephen Byrd

4. Cursor’s $60B Deal, DeepSeek V4 & the Death of the AI Moat

This Week in AI

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 14 m)

Topics: AI | Product | Startups | Strategy | Venture Capital

Founders from Factory AI, LiveKit, and Hebbia analyse Cursor’s $60B SpaceX option deal, DeepSeek V4’s cost edge, and AI moats collapsing.

● AI coding agents outperform traditional development approaches through superior capabilities

● Voice interface adoption emerges as default interaction method for AI applications

● LLM commoditisation parallels RAM market dynamics, eroding competitive moats

5. Chief Operating Officer of IBM Infrastructure, Barry Baker, oversees the world’s most critical systems – including the iconic IBM Z.

Making Data Simple

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (44 m)

Topics: AI | Data | Leadership | Operations | Technology

Barry Baker, IBM Infrastructure COO, explains why mainframe modernisation misconceptions miss the point and how AI acceleration on Z drives enterprise transformation.

● Mainframe platforms deliver eight nines availability and process 25 billion transactions daily—moving workloads to cloud typically costs more due to fragmented security and resiliency.

● IBM Spire accelerator enables fraud detection in under one millisecond per transaction, eliminating latency constraints that previously required off-platform processing.

● Successful AI adoption requires breaking large initiatives into smaller, measurable pieces with contained blast radius, prioritising storage strategy and post-quantum cryptography inventory now.

“The real magic is going to be how you as an enterprise can take your data, your business data, and actually figure out how to inject that into your workflows.” - Barry Baker

1. OpenAI co-founder Greg Brockman charts AI's parabolic acceleration towards AGI, sharing the lab's origin story, internal crises, and bold technical roadmap.

2. Canva CEO Melanie Perkins outlines the pivot to AI enterprise software, where concepts generate editable designs and enterprise revenue surges past $500M.

3. Snap CEO Evan Spiegel envisions AR glasses supplanting smartphones through spatial computing, AI-generated code, and close-friend messaging prioritisation.

4. Anthropic's Cat Wu, Head of Product for Claude Code, demonstrates shipping AI features in days via rapid iteration and sharp product taste amid evolving models.

5. Solo founder Tibo Louis-Lucas bootstraps five AI products to $1M+ monthly revenue by pivoting on user hacks, charging premium from day one, and targeting niche SEO.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. OpenAI Co-Founder: AI Goes Parabolic! Here’s What’s Next | Greg Brockman

The Knowledge Project

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 12 m)

Topics: AI | Startups | Technology

OpenAI co-founder Greg Brockman explains AI’s parabolic acceleration and AGI path in this insider account.

● Greg Brockman describes leaving Stripe to pursue a lifelong mission in AI, co-founding OpenAI after a pivotal dinner with Sam Altman where they concluded it was still possible to build a world-changing AI lab despite DeepMind’s dominance.

● Greg recounts OpenAI’s early formation, including convincing top researchers to join, defining a long-term technical roadmap focused on reinforcement learning and unsupervised learning, and using an offsite in Napa to crystallise the lab’s mission and momentum.

● Greg details the internal crisis in which leadership changes led to mass employee backlash, an attempted spin-out with Sam and close collaborators, a staff petition that crashed Google Docs, and ultimately a fragile but hopeful reconciliation, including mending a deeply strained relationship with co-founder Ilya.

“We’re going to be hitting a phase soon where the AI will also come up with its own research ideas and test those out, run experiments, and so I think that the speed of iteration and innovation is going to continue to increase as a result of what we’re producing.” - Greg Brockman

2. Canva’s CEO on its big pivot to AI enterprise software

Decoder with Nilay Patel

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 14 m)

Topics: AI | Leadership | Product | Startups

Canva CEO Melanie Perkins explains the pivot from design platform with AI tools to AI platform with design tools, launching Canva AI 2.0 for end-to-end workflows.

● Canva advances from pixels and objects to concept layer, where users input ideas for AI-generated designs editable via drag-and-drop.

● Enterprise revenue hits $500M of $4B total, with 95% Fortune 500 adoption and AI 2.0 targeting deeper integration via connectors to Gmail and Slack.

● AI acts as creative partner for iterative editing, reducing manual work while preserving collaboration and customisation in one platform.

“AI should accelerate your vision and creativity, not override it.” - Melanie Perkins

3. What comes after smartphones, with Snap CEO Evan Spiegel

Cheeky Pint

Listen on: Spotify | Apple Podcasts | Podlink (1 h 4 m)

Topics: AI | Hardware | Product | Startups | Technology | UX/UI

Snap CEO Evan Spiegel outlines how AR glasses replace smartphones by enabling spatial computing and shared real-world experiences.

● Snapchat glasses deliver Vision Pro-level capability in everyday eyewear, shifting computing from isolating screens to the world.

● Over two-thirds of new code at Snap is AI-generated, accelerating bespoke software via Lens Studio for custom experiences.

● Snap prioritises close-friend messaging over broad networks, avoiding anti-network effects and boosting user well-being.

“if it’s not 10 times better than the next best alternative, then there’s no point in investing in it.” - Evan Spiegel

4. How Anthropic’s product team moves faster than anyone else | Cat Wu (Head of Product, Claude Code)

Lenny’s Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 26 m)

Topics: AI | Leadership | Product | Startups

Cat Wu, Head of Product for Claude Code at Anthropic, explains how her team ships features in days instead of months.

● Cat explains how she partners with tech lead Boris to translate his AGI-scale product vision into a 3–6 month execution roadmap while keeping cross-functional teams tightly aligned.

● She argues that AI-native PMs must optimise for extreme iteration speed—shipping meaningful features weekly or faster—and focus on eliciting maximum capability from today’s models rather than designing only for hypothetical future AGI.

● Cat emphasises that as code becomes cheap, the most valuable emerging PM skill is strong product taste: knowing what to build, in what order, and how to make those choices amid rapidly changing AI capabilities.

“The timelines for a lot of our product features have gone down from six months to one month and sometimes to even one day.” - Cat Wu

5. How This Solo AI Founder Bootstrapped 5 Products to 1M+ / Month | Tibo Louis-Lucas

Behind the Craft

Listen on: Spotify | Apple Podcasts | Podlink (44 m)

Topics: AI | Marketing | Product | Startups

Solo founder Tibo Louis-Lucas bootstraps five AI products to over $1M monthly revenue.

● Pivot when users twist the product for unintended uses, signalling stronger opportunities.

● Charge $50-100/month from day one for high-quality customers and low churn.

● Build SEO tools targeting niche queries to drive recurring traffic.

“I’m convinced right now that just one person can do the job of 20 compared to like five years ago.” - Tibo Louis-Lucas

1. Replit CEO Amjad Masad explains how vibe coding with AI lets non-coders build MVPs in hours, spot trends for unique ideas, and escape the rat race through startup equity.

2. Samsung CDO Mauro Porcini outlines an AI design blueprint centred on humanity’s four pillars—live longer, better, loud, and on—to craft personalised tech that follows meaning.

3. DoorDash CEO Tony Xu breaks down conquering restaurant economics by prioritising retention over discounts, outsmarting rivals, and blending robots with drones for future delivery.

4. Vantor CPO Peter Wilczynski demonstrates mapping 100M+ sq km of Earth in 3D, embedding satellite data into hyperdimensional models for AI-powered spatial intelligence and GPS-free navigation.

5. Physical Intelligence co-founder Kuan Vuong shows how cross-embodiment foundation models deliver robotics’ GPT moment, slashing hardware costs with zero-shot tasks and workflow mastery.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. Replit’s CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI

a16z Podcast

Listen on: Spotify | Apple Podcasts | Podlink (1 h 39 m)

Topics: AI | Product | Programming | Startups | Venture Capital | Vibe Coding

Replit CEO Amjad Masad reveals how AI empowers non-coders to ship software fast and build wealth via ownership, debunking AI doomsday fears.

● Observe problems around you to generate unique ideas tied to trends, then use AI to build MVPs in hours.

● Lack of coding experience advantages entrepreneurs by prioritising customer needs, marketing, and revenue over syntax.

● Build equity through startups or early equity in high-growth companies rather than salaries to escape the rat race.

“I think it’s the easiest time to get rich in the history of capitalism, but certainly in the history of the internet.” - Amjad Masad

2. A first look at Samsung’s blueprint to win the AI era, with Mauro Porcini

Masters of Scale with Reid Hoffman

Listen on: Spotify | Apple Podcasts | Podlink (36 m)

Topics: AI | Hardware | Leadership | Product | Strategy | UX/UI

Samsung CDO Mauro Porcini outlines their AI-driven design blueprint to prioritise humanity over commoditised tech.

● Designers act as humanity’s voice via four pillars: live longer, better, loud, and on.

● Blend human-AI perspectives to create original designs, avoiding AI commoditisation.

● Shift from form follows function to form and function follow meaning for personalised tech.

“Ultimately, AI can do the most human thing of all, give us back the happiness we’ve lost over time.” - Mauro Porcini

3. The economics and trends of the restaurant industry, with Tony Xu of DoorDash

Cheeky Pint

Listen on: Spotify | Apple Podcasts | Podlink (1 h 27 m)

Topics: Product | Startups

Discover how DoorDash CEO Tony Xu conquered brutal restaurant economics, outsmarted Google, and refunded 40% of cash to rescue the company.

● DoorDash prioritised retention over discounts, achieving higher frequency without heavy marketing spend.

● Restaurants shift towards service or manufacturing extremes due to rising labour costs and staffing challenges.

● Future delivery mixes DOT robots for dense urban orders and drones for longer distances.

“We refunded everyone that cost us over 40% of the bank account.” - Tony Xu

4. This Company Mapped the Entire World in 3D. Here’s Why.

The Neuron: AI Explained

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 3 m)

Topics: AI | Product | Science & Research | Startups | Technology

Peter Wilczynski, Vantor CPO, explains their 100M+ sq km 3D Earth model enabling AI to reason about the physical world.

● Vantor embeds satellite imagery into hyperdimensional space, translating pixels to human-readable entities like cars and trees.

● Tensor Globe platform fuses multi-source data into a daily-updated ground truth world model for simulations.

● Spatial intelligence grounds generative world models in reality, powering GPS-free navigation and AR experiences.

“We have over 100 million square kilometers... with 50 centimeter resolution across the whole world.” - Peter Wilczynski

5. The GPT Moment for Robotics Is Here

Y Combinator

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (49 m)

Topics: AI | Hardware | Robotics | Startups

Physical Intelligence co-founder Kuan Vuong explains how foundation models enable the GPT moment for robotics, controlling any robot for any task.

● Cross-embodiment training outperforms specialists by 50%, enabling zero-shot tasks that once needed hundreds of hours of data.

● Cloud-hosted models run real-time via API queries and action chunking, slashing robot hardware costs.

● Vertical robotics startups succeed by understanding workflows, using cheap hardware, mixed autonomy to break even, then scaling.

“the equation... for starting a robotic business has changed.” - Kuan Vuong

The podcast episode recommendations for today are:

1. NVIDIA product marketing manager Nick Harrigan explains how AI accelerates quantum error correction and unlocks drug discovery applications with high-throughput decoders processing terabytes per second.

2. Apple's leaked N50 AI glasses offer a displayless edge with Siri 2.0 and vertical supply chain control to challenge Meta's wearable lead and build a distributed sensor ecosystem.

3. ElevenLabs cofounder Mati Staniszewski breaks down voice AI models using transformers and diffusion to generate expressive speech, while outlining why conversational agents still falter on turn-taking.

4. Figma CEO Dylan Field argues taste and craft remain essential amid AI tools, showing designers how to iterate raw outputs into intentional work on a visual-first platform.

5. Three AI founders argue open agents and verified superintelligence will reshape software by enabling parallel model swaps and formal code proofs to catch elusive bugs. Pick an episode, press play, lace up and get moving.

   Get 5 x podcast recommendations in AI, tech, startup, and product. Sent weekly.

   Podcast Recommendations

   1. How AI Will Change Quantum Computing

   NVIDIA AI Podcast

   Listen on: Spotify | Apple Podcasts | Podlink (31 m)

   Topics: AI | Hardware | Science & Research | Technology

   NVIDIA product marketing manager Nick Harrigan explains how AI is accelerating quantum computing, from error correction to new applications in drug discovery and materials science.

   ● AI can dramatically speed up quantum error correction by running high‑throughput decoders that process terabytes of data thousands of times per second.

   ● Open AI models like NVIDIA Ising help quantum hardware builders calibrate devices and decode errors, lowering the barrier to practical quantum systems.

   ● Generative models and agentic workflows may soon design and compile quantum algorithms, helping researchers discover new quantum applications humans struggle to conceive.

   “In some cases quantum computing can give us a kind of exponential or even like a very strong polynomial advantage over a normal computer.”

   ---

   2. Behind Apple’s AI Smart Glasses: Their Last Chance (and Greatest Hope)

   Limitless Podcast

   Listen on: Spotify | Apple Podcasts | Podlink (25 m)

   Topics: AI | Hardware | Product | Technology

   Apple’s leaked N50 AI glasses represent the company’s critical opportunity to dominate wearable AI by combining displayless design, advanced Siri integration, and vertical supply chain control against Meta’s Ray-Ban lead.

   ● Apple’s N50 glasses feature displayless design with dual cameras, voice-based control, and integration with Siri 2.0 powered by Google’s Gemini model for contextual AI assistance across the Apple ecosystem.

   ● Apple’s three-pronged AI wearable strategy—glasses, camera-equipped AirPods, and pendant device—creates a distributed sensor suite that feeds visual context into Apple Intelligence for hands-free interactions.

   ● Apple’s in-house manufacturing using acetate frames and proprietary chips provides competitive advantage over Meta, Google, and Snap, who rely on external partners like EssilorLuxottica and lack integrated software ecosystems.

   “The next great compute platform is going to be on your face. It’s glasses. Everyone’s building glasses.”

   ---

   3. The world of voice AI, with Mati Staniszewski of ElevenLabs

   Cheeky Pint

   Listen on: Spotify | Apple Podcasts | Podlink (1 h)

   Topics: AI | Product | Startups | Technology

   ElevenLabs cofounder Mati Staniszewski explains how voice AI models work, why conversational agents still haven’t passed the Turing test, and how the company scaled to $450 million ARR.

   ● Voice models predict phonemes using transformer and diffusion architectures, then decode context and speaker characteristics to generate emotionally expressive speech without hard-coded parameters.

   ● Conversational voice agents remain unsolved: they require orchestrating speech-to-text, LLM reasoning, and text-to-speech whilst handling turn-taking, tool calls, and authentication gracefully.

   ● ElevenLabs grew 100 million in net new ARR this quarter by offering self-serve access, pay-as-you-go pricing, and deploying small technical teams across enterprise customer organisations.

   “High agency people are the winners of the advances in AI and within organisations, low agency people will lose out.” - John Collison

   ---

   4. Figma CEO on How Anyone Can Get Good at Design in the AI Era

   Behind the Craft

   Listen on: Spotify | Apple Podcasts | Podlink (41 m)

   Topics: AI | Product | Startups | Technology | UX/UI

   Figma CEO Dylan Field explains how AI reshapes design, why taste and craft still matter, and how anyone can get better at design in the AI era.

   ● Taste is about clear preferences and articulating what you are and are not going for, while craft is pushing work to fit together across all levels of abstraction.

   ● AI outputs are starting points, not final products; designers must iterate, diverge, and converge to shape raw outputs into intentional, high‑quality work.

   ● Figma is evolving into a visual-first platform where design can act like code, enabling pull requests to production and tighter loops between design, code, and customer feedback.

   “Taste is really about navigating the possibilities of what’s out there and having preferences that are really clear that you can articulate.” - Dylan Field

   ---

   5. What’s Left for Humans When AI Builds Everything?

   This Week in AI

   Listen on: Spotify | Apple Podcasts | Podlink (1 h 27 m)

   Topics: AI | Automation | Productivity | Programming | Startups

   Three AI founders argue that open agents and verified superintelligence will reshape software, work, and human purpose in the next few years.

   ● Open agent infrastructure lets developers swap models and run hundreds of agents in parallel, reducing lock‑in to closed platforms like Anthropic or OpenAI.

   ● An AI mathematician that formally verifies code and proofs can catch edge‑case bugs and make superintelligence meaningful rather than probabilistic.

   ● Enterprise AI systems are shifting from fine‑tuning small models to using large models with smart context and memory, while open source and smaller models still matter for specific workflows.

1. Travis Kalanick unveils Atoms, his bold physical AI venture rebranding stealth food infrastructure into robotics and mining automation.

2. Mukund and Madhav Jha, founders of Emergent, detail building a global AI startup from India that empowers non-technical users to create 7 million production-ready apps in eight months.

3. Dr. Caroline Chung explains how digital twins personalise cancer radiation treatments using patient genetics, blood tests, and MRI data for precise, predictive healthcare.

4. Quantum expert Karina Leiner reveals how quantum computing supercharges AI with superior probability sampling and denoising for medical breakthroughs classical systems miss.

5. Elena Verna shares Lovable's playbook to $400M ARR, prioritising employee-led trust-building and daily releases over paid marketing in AI growth.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. Uber Founder Travis Kalanick is Back with a New AI Startup

TBPN

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (58 m)

Topics: AI | Robotics

Travis Kalanick unveils Atoms, his physical AI venture rebranding stealth food infrastructure into robotics and mining automation.

● Master LTV to CAC in B2B sales funnels.

● Build network effects via owned real estate.

● Systematise fundraising with scalable storytelling.

“A meal that’s prepared and delivered to you so efficient that it starts to approach the cost of going to the grocery store.” - Travis Kalanick

2. Building A Global AI Startup From India

Y Combinator Startup Podcast

Listen on: Spotify | Apple Podcasts | Podlink (40 m)

Topics: AI | Product | Startups | Technology

Mukund and Madhav Jha, founders of Emergent, discuss how their AI platform enables non-technical users to build production-ready apps at scale, with 7 million apps created in eight months.

● Emergent prioritises shipping production-ready software by replicating best engineering practices: code reviews, testing, debugging, deployment, and security.

● 80% of users are non-technical; the platform uses multi-agent architecture with long-term memory that learns across sessions to improve performance over time.

● Second-mover advantage allowed Emergent to learn from competitors and reimagine the entire platform for end-to-end production, not just front-end prototyping.

“People who are really close to problem domain expert but have been blocked by technology barrier are using Emergent to build these things out.”

3. Could a ‘digital twin’ help you get better health care?

Science Friday

Listen on: Spotify | Apple Podcasts | Podlink (18 m)

Topics: AI | Science & Research | Technology

Dr. Caroline Chung explains how digital twins could personalise cancer radiation and predict treatments using patient data.

● Digital twins enable personalised healthcare by simulating individual patient treatments using genetics, blood tests, and MRI data.

● In silico clinical trials replace animal testing by modelling drug effects on patient-specific digital twins before human trials.

● AI-driven medicine requires individual patient details, not statistical averages, to effectively treat the patient in front of clinicians.

“We can embrace technology, but maintain the humanity of medicine.” - Dr. Caroline Chung

4. Quantum Computing and AI – A Superpower in the Making?

Transform NOW

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (36 m)

Topics: AI | Science & Research | Technology

Quantum expert Karina Leiner reveals how quantum computing accelerates AI without worsening hallucinations, unlocking industry breakthroughs.

● Quantum boosts generative AI models via better probability sampling.

● Quantum denoising enhances medical image analysis accuracy.

● Quantum linear solvers detect patterns classical AI misses.

“quantum and AI can go hand in hand and they can actually be a new superpower.” - Karina Leiner

5. Inside Lovable’s $400M ARR Growth Machine

The Twenty Minute VC

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 9 m)

Topics: AI | Leadership | Marketing | Product | Startups | Strategy | Venture Capital

Elena Verna reveals how Lovable hit $400M ARR by prioritising trust over features in AI growth.

● Build trust via employee-led social posting.

● Avoid paid marketing under 10% in year one.

● Launch daily releases for constant buzz.

“For any founder in the first year, investing in paid as the means of growth is a death trap.” - Elena Verna

1. Zach Yadegari, the 19-year-old who built a $50M AI app in high school, shares how warm introductions and founder advice led to selling Cal AI for a massive exit after $30M revenue.

2. Leopold Aschenbrenner, the 24-year-old investor who turned $1B into $5.5B, explains pivoting from NVIDIA to energy infrastructure like Bloom Energy and CoreWeave for AI dominance.

3. Google VP Robby Stein unveils AI Mode’s transformation of search into conversational tools, delivering personalised plans to 1.5 billion users with 65% multimodal growth.

4. Robinhood co-founder and CEO Vlad Tenev reveals surviving an 80% valuation crash by shifting to lean operations and leveraging AI for breakthrough problem-solving.

5. Xero SVP Lisa Huang, creator of Gemini Gems, demonstrates building custom AI clones from PRDs, emails, and research transcripts to supercharge product manager productivity.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. I built a $50M AI app in high school (and just sold it for...)

My First Million

Listen on: Spotify | Apple Podcasts | Podlink (1 h 10 m)

Topics: AI | Product | Startups

19-year-old Zach Yadegari sold his AI calorie-tracking app Cal AI to MyFitnessPal after $30M revenue.

● Zach Yadegari sold CalAI after achieving $30 million revenue at age 19

● Warm introductions and experienced founder advice proved critical to acquisition success

● Self-investment and future ventures prioritised over immediate capital deployment post-sale

“Learn the 20% that gets you the 80% of results.” - Zach Yadegari

2. Leopold Aschenbrenner 2.0: The 24 Year-Old Who Made $4.5B Investing in These Companies

Limitless: An AI Podcast

Listen on: Spotify | Apple Podcasts | Podlink (26 m)

Topics: AI | Technology

24-year-old Leopold Aschenbrenner grew $1B to $5.5B in AI investments by pivoting to overlooked energy infrastructure.

● Exit NVIDIA and chips for energy plays like Bloom Energy.

● Bet big on CoreWeave for AI compute hosting.

● Repurpose Bitcoin miners for AI data centre power.

“Bitcoin mining companies are going to either sell their rights and their permits or just pivot to AI data centers.”

3. How AI Is Rewriting Google Search with Robby Stein (Google Search)

Superhuman AI: Decoding the Future

Listen on: Spotify | Apple Podcasts | Podlink (37 m)

Topics: AI | Product | Technology

Google VP Robby Stein reveals AI Mode’s shift to conversational search, unlocking personalised plans and agentic actions across life’s contexts.

● 1.5 billion users utilise AI Overviews.

● Multimodal search grows 65% year-over-year.

● Developed AI Mode from concept to launch in one year.

“It’s a real fundamental shift in how people use search.” - Robby Stein

4. Inside the Mind of Robinhood Co-Founder Vlad Tenev

The Knowledge Project

Listen on: Spotify | Apple Podcasts | Podlink (1 h 50 m)

Topics: AI | Startups | Venture Capital

Robinhood CEO Vlad Tenev reveals GameStop crisis truths and fintech pivots amid 80% valuation crash.

● Surviving 80% market crash requires transitioning from hyper-growth bloat to lean operations

● Storytelling and CEO involvement essential for coherent product messaging across platforms

● AI problem-solving capabilities advancing from competition maths to solving unsolved mathematical problems

“If you can figure out how to solve a math problem, you could solve pretty much any problem.” - Vlad Tenev

5. Gemini Gem Masterclass From the Creator Lisa Huang

The Growth Podcast

Listen on: Spotify | YouTube | Podlink (52 m)

Topics: AI | Product | Startups

Lisa Huang, Gemini Gems creator and Xero SVP, reveals custom AI tools maximising PM productivity.

● Build writing clone from PRDs and emails.

● Create strategy advisor with company docs.

● Synthesise user research from transcripts.

“There’s three must-have gems for every product manager. Let’s call them the writing clone, the product strategy advisor, and the user research synthesizer.” - Lisa Huang

1. Wix co-founder Nadav Abrahami shares his AI prototyping workflow that takes product managers from idea to validated features without developers.

2. Claude design lead Jenny Wen details AI-driven changes replacing rigid design processes with rapid execution and long-term vision-setting.

3. Google DeepMind’s Logan Kilpatrick unpacks how Gemini 3 Flash beats its Pro predecessor on benchmarks while running three times faster at quarter the cost.

4. Alibaba.com president Kuo Zhang explains how AI agent Accio automates B2B sourcing, compressing weeks of global trade work into minutes.

5. Poetic co-CEO Ian Fisher, ex-DeepMind, reveals recursive self-improving AI harnesses that outperform frontier models at low cost.

Pick an episode below, press play, lace up and get moving.

Podcast Recommendations

1. How to AI Prototype Well | Masterclass from $5.5B Founder, Nadav Abrahami (Wix)

Product Growth Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 17 m)

Topics: AI | Product | Startups

Wix co-founder Nadav Abrahami reveals AI prototyping workflow that accelerates PMs from idea to validated features without devs.

● Build 3-4 divergent solutions; single prototypes miss edge cases.

● Test prototypes with engaged users before engineering handoff.

● Lock down problem, user story, solution shape first.

“If you can’t build a production app without AI, it’s going to be really hard to build a production app with AI.” - Nadav Abrahami

2. The design process is dead. Here’s what’s replacing it.

Lenny’s Podcast: Product | Growth | Career

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 17 m)

Topics: AI | Product

Jenny Wen (Claude design lead) reveals AI-forced shifts replacing rigid design processes with rapid execution and vision-setting.

● Shift mocking from 60-70% to 30-40% of time.

● Focus on execution support and 3-6 month prototypes.

● Hire block generalists, deep specialists, crack new grads.

“This design process that designers have been taught, we sort of treat it as gospel. That’s basically dead.” - Jenny Wen

3. Gemini 3 Flash (Smartest, Cheapest AI) with Google DeepMind’s Logan Kilpatrick

The Neuron: AI Explained

Listen on: Spotify | Apple Podcasts | Podlink (1 h 59 m)

Topics: AI | Product | Technology

Logan Kilpatrick from Google DeepMind explains how Gemini 3 Flash outperforms its Pro predecessor whilst running 3x faster at one-quarter the cost, unlocking new use cases for developers and knowledge workers.

● Flash model outperforms Pro on most benchmarks, achieving 78% on SWE-bench Verified for agentic coding tasks.

● Agents, multimodal understanding, and vibe coding become economically feasible at Flash pricing; code generation could become free.

● Faster iteration speed keeps users in flow state; ambitious prompting with Flash yields better results than constrained requests.

“Go and be ambitious with this model... make use of it, start building something.” - Logan Kilpatrick

4. AI Agents and the Future of Global Trade with Alibaba’s Kuo Zhang

NVIDIA AI Podcast

Listen on: Spotify | Apple Podcasts | Podlink (33 m)

Topics: AI | Automation | Product | Startups

Alibaba.com president Kuo Zhang reveals how AI agent Accio automates B2B sourcing, slashing weeks to minutes for global trade.

● AI agents like Accio automate complex B2B sourcing, compressing weeks into minutes

● AI-native commerce lowers barriers for solo entrepreneurs and small-to-medium enterprises

● Global trade reshaping through intelligent agent automation and streamlined procurement processes

“Previously, they may take weeks, even months to finish this sourcing list. Now using Axio, it can be finished in hours or in minutes.” - Kuo Zhang

5. The Fastest Path To Super Intelligence

Y Combinator

Listen on: Spotify | Apple Podcasts | Podlink (20 m)

Topics: AI | Startups | Technology

Ian Fisher, Poetic co-CEO ex-DeepMind, unveils recursive self-improving AI harnesses outperforming frontier models cheaply.

● Build reasoning harnesses outperforming base models.

● Layer recursive self-improvement atop LLMs.

● Automate prompt engineering boosting 5% to 95% performance.

“recursive self-improvement is this, you know, kind of the holy grail of AI, where the AI is making itself smarter.” - Ian Fisher

1. OpenClaw's AI agents with shared memory dismantle startup knowledge silos, unifying Slack, Notion, and email data for recursive marketing funnel analysis and proactive skill iteration.

2. Bestselling author Michael Pollan argues consciousness demands embodied vulnerability and suffering, as large language models miss the global workspace competition of human brain modules.

3. Bizzy CEO Corinna Stukan shares a metrics one-pager framework to align product work with revenue goals, adapting prioritisation for growth, acquisition, or cost-control phases.

4. Unicorn investor Elad Gil, backer of Airbnb and OpenAI, predicts AI will enable solo billion-dollar ventures by slashing enterprise workflows and targeting overlooked niches.

5. Google's Lyria 3 crafts full 30-second songs from text prompts or images, complete with SynthID watermarking and tools like Pomelli for instant product photoshoots.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. Kill Your Startup’s Knowledge Chaos with OpenClaw

This Week in Startups

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 18 m)

Topics: AI | Automation | Product | Productivity | Startups

Learn how AI agents with shared memory break down startup silos and transform chaotic internal communication into coordinated action.

● Build recursive agents analysing full marketing funnels.

● Unify company data across Slack, Notion, email for instant insights.

● Iterate skills proactively via shared memory files.

“I think we’ll be able to automate 10% of our work a week, doubling our efficiency.” - Jason Calacanis

2. Can AI Achieve Consciousness? — With Michael Pollan

Big Technology Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (52 m)

Topics: AI | Science & Research | Technology

Bestselling author Michael Pollan debates if AI can ever achieve true consciousness, revealing human mind’s unique essence.

● Consciousness requires feeling grounded in bodily vulnerability and suffering capacity.

● Global workspace theory explains how competing brain modules compete for conscious attention.

● Current large language models lack embodied experience to generate authentic feelings.

“Feelings depend on things that I don’t think computers have, which is to say mortal bodies that can suffer.” - Michael Pollan

3. How to align product work to business goals

The Product Experience

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (37 m)

Topics: Leadership | Product | Startups

Corinna Stukan (CEO, Bizzy) reveals how product leaders connect daily work to revenue goals, avoiding misalignment traps.

● Create metrics one-pager linking company goals to product indicators.

● Adapt prioritisation to growth, acquisition, or cost-control modes.

● Frame initiatives highlighting commercial impact over UX improvements.

4. Elad Gil backed 40 unicorns. This is next.

Mixergy

Listen on: Spotify | Apple Podcasts | Podlink (45 m)

Topics: AI | Startups | Venture Capital

Elad Gil, unicorn investor in Airbnb and OpenAI, reveals AI’s power to spawn billion-dollar solo ventures like Minecraft.

● AI empowers millions to build software solo.

● Custom AI tools slash enterprise workflows dramatically.

● Big companies overlook niches ripe for disruption.

“It’s going to put the power of building things in the hands of millions of people who couldn’t do it before.” - Elad Gil

5. Google’s Lyria 3: The Music AI that Changes Everything

Limitless Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (24 m)

Topics: AI | Product | Technology

Google’s Lyria 3 generates full songs from prompts or images, revolutionising creator tools with demos of Kanye-style anthems and snowy vibes.

● Generate 30-second songs instantly from text prompts.

● Create product photoshoots from single images via Pomelli.

● Detect AI music with SynthID watermarking.

“this could replace a music series entirely, at least for 30-second excerpts for TikTok.”

1. Ankit Shula from The Growth Podcast reveals how product managers can build a three-layer metrics framework to evaluate AI models and ship reliable features without failure.

2. Patrick Collison, Stripe’s co-founder, explains how prioritising enduring APIs and unifying abstractions early transformed payment infrastructure and reshaped global commerce.

3. Andrew Salisbury built a $42M coffee business by lab-testing 59 brands and investing two years in R&D to eliminate hidden toxins competitors ignore.

4. Figma CEO Dylan Field shares how the platform achieved 40% growth to $304M, with AI-powered design-code pathways enabling non-designers to create files at scale.

5. Allan Thygesen, Docusign’s CEO, warns of critical AI risks in contract summarisation and generation, outlining guardrails to keep humans in the loop for high-stakes decisions.

Pick an episode below, press play, lace up and get moving.

Podcast Recommendations

1. AI Evals Explained Simply by Ankit Shula

The Growth Podcast

Listen on: Spotify | YouTube | Apple Podcasts (1 h 3 m)

Topics: AI | Product

Ankit Shula shares a masterclass on AI evals, revealing how PMs tame non-deterministic models to ship reliable features without failure.

● Build three-layer metrics framework: system, quality, business.

● Implement LLM-as-judge with 1-5 rubric scale.

● Alert on hallucinations exceeding 5%.

“Your AI feature fails not because of the model, but because you didn’t evaluate it.” - Ankit Shula

2. Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

The a16z Show

Listen on: Spotify | Apple Podcasts | Podlink (53 m)

Topics: AI | Product | Startups

Patrick Collison reveals how Stripe’s API simplicity became the internet’s payment infrastructure, reshaping global commerce.

● Fix errors mid-request in interactive environments.

● Prioritise enduring APIs for business outcomes.

● Unify abstractions early to enable flexibility.

“We just didn’t think that the regulatory and partnership/banking barriers were actually that bad.” - Patrick Collison

3. We Built a $42M Business by Reinventing Coffee | Purity Coffee

The Foundr Podcast with Nathan Chan

Listen on: Spotify | Apple Podcasts | Podlink (48 m)

Topics: Product | Science & Research | Startups

Discover how Andrew Salisbury transformed coffee into a $42M health revolution by eliminating hidden toxins most brands ignore.

● Lab-tested 59 brands to validate superior antioxidants.

● Invested 2 years in R&D before first sale.

● Achieved 50% margins by prioritising product over pricing.

“focus on being the best in the world at one thing matters more than anything in business.” - Andrew Salisbury

4. Post Earnings with Figma CEO Dylan Field

TBPN

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (21 m)

Topics: AI | Product | Startups

Figma CEO Dylan Field reveals Q4’s 40% growth to $304M and AI-powered design-code pathways post-earnings.

● Figma Make users grew 70% quarter-over-quarter.

● 60% of Figma Make files created by non-designers.

● Taste differentiates in agent-driven design world.

“60% of files created in Figma Make are non-designers at this point.” - Dylan Field

5. Docusign’s CEO on the dangers of trusting AI to read, and write, your contracts

The Verge - Decoders

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 9 m)

Topics: AI | Product | Startups | Technology

Docusign CEO Allan Thygesen warns of AI risks in contract summarisation and generation, sharing guardrails for trust.

● Extract insights from stored agreements automatically.

● Apply risk scoring to flag contract deviations.

● Keep humans in loop for high-stakes decisions.

“The agreement problem is fundamentally unsolved but Docusign is in the best position to capture that opportunity.” - Allan Thygesen

1. Boris Cherny, creator of Claude Code at Anthropic, shares how building for models six months ahead boosted engineer productivity 70% and now powers 4% of public commits.

2. Anto pitches Cosmic Brain AI on The Pitch, unveiling VR glasses that let anyone train robots from video demos, slashing engineering costs with a skills marketplace.

3. Google principal engineer Taylor Mullen explains shipping 150 Gemini CLI features weekly by granting AI agents full OS access while enforcing strict human oversight.

4. Kavak CEO Carlos Garcia Otati discusses rebuilding his company around AI agents that now handle 90% of customer interactions after enduring initial performance dips.

5. Limitless Podcast rigorously tests OpenClaw across user types, spotlighting FelixBot’s $41,000 weekly earnings alongside critical security risks and safer alternatives.

Pick an episode below, press play, lace up and get moving.

Podcast Recommendations

1. How Anthropic Built Claude Code (w/ Boris Cherny)

Y Combinator

Listen on: Spotify | Apple Podcasts | Podlink (50 m)

Topics: AI | Product | Productivity | Programming | Technology

Boris Cherny, creator of Claude Code at Anthropic, reveals how building for future models—not today’s—transformed coding productivity by 150% and may eliminate the software engineer job title entirely.

● Build for the model six months ahead, not today’s capabilities, to avoid being leapfrogged by competitors.

● Claude Code’s terminal design emerged accidentally from latent user demand, not a master plan.

● Anthropic’s productivity per engineer grew 70% despite doubling team size; 4% of all public commits now use Claude Code.

“Don’t build for the model of today, build for the model six months from now.” - Boris Cherny

The Pitch

Listen on: Spotify | Apple Podcasts | Podlink (41 m)

Topics: AI | Product | Robotics | Startups | Venture Capital

Anto pitches Cosmic Brain AI, software that democratises robot training via VR glasses and video, enabling anyone to teach robots new skills without millions in engineering costs.

● Vision Language Action models translate human video into robot motor movements, enabling one-shot learning from single demonstrations.

● Marketplace model lets developers sell trained robot skills as APIs, generating revenue per robot usage hour across any hardware brand.

● B2B focus on airlines, automotive, and warehouses proves faster traction than consumer robotics; six-month follow-up shows pre-seed closed at $1M.

“We are building the cursor for robotics. This is the future of robot training.” - Anto

3. How Google’s Gemini CLI Creator Ships 150 Features a Week

The Neuron: AI Explained

Listen on: Spotify | Apple Podcasts | Podlink (56 m)

Topics: AI | Product | Productivity | Programming

Taylor Mullen, Google principal engineer and Gemini CLI creator, reveals how his team ships 100–150 features weekly by giving AI agents full OS access instead of confining them to text editors.

● Gemini CLI enables agentic search through codebases using grep and file reading rather than embeddings, mimicking how human developers solve problems.

● Policy files and hard-coded permission checks prevent agents from executing unauthorised actions, maintaining human oversight at every critical step.

● The Ralph Wiggum technique—refeeding outputs into fresh contexts iteratively—refines AI solutions and enables longer autonomous workflows without derailing.

“Right now, out of the default on our team, everyone’s 10X. So we’re not thinking about better anymore, because the 10X is almost the new normal.” - Taylor Mullen

4. From Copilots to Agents: Rebuilding the Company Around AI

a16z Podcast

Listen on: Spotify | Apple Podcasts | Podlink (1 h)

Topics: AI | Automation | Leadership | Product

Kavak CEO Carlos Garcia Otati reveals replacing copilots with AI agents handling 90% of customer interactions after a painful year of flat growth.

● Build ontology first for agent communication.

● Deploy agents on hardest funnels initially.

● Endure performance dips for AI superiority.

“When you’re building AI, the first thing that you need to build is the brakes of the system.” - Carlos Garcia Otati

5. Inside OpenClaw: Should You Actually Use It? Probably Not.

Limitless Podcast

Listen on: Spotify | Apple Podcasts | Podlink (23 m)

Topics: AI | Automation | Cybersecurity | Product | Technology

Hosts test OpenClaw’s real-world capabilities across three user archetypes, revealing which use cases deliver value and which require patience.

● FelixBot generated $41,000 weekly through autonomous book creation, token trading, and skill marketplace transactions.

● Security risks include brute-force attacks, credential exposure, and prompt injection vectors requiring sandboxed deployment.

● Claude Cowork offers safer alternative; wait for OpenAI and Anthropic’s curated versions launching within three to six months.

“Imagine giving ChatGPT access to your wallet, your medical records, and allowing it to run loose in the world.”

• ByteDance's Seedance 2.0 vaults past Sora and Veo with 90% usable output, as Leveraging AI explores deepfake fraud risks and AI's surprising burnout paradox.

• ElevenLabs VP Sales Carles Reina reveals scaling to $330M ARR through 20x quotas, ruthless outbound tactics, and prioritising road time over office hours.

• Sequoia CEO coach Brian Halligan shares why starting companies is easier than ever yet scaling demands spicy hires, Red Sox-style teams, and the LOCKS CEO framework.

• Serial entrepreneur John Osher recounts transforming spinning lollipops into Spinbrush, a $475M P&G acquisition, via demand-based pricing and brand integrity scrapping 400,000 defects.

• Novartis CEO Vasant Narasimhan details spinning off units to unlock $180B value, focussing on cell/gene therapies for autoimmune cures and AI slashing drug timelines by years.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. China vaults ahead: C-Dance 2.0 leaves Sora & Veo in the dust

Leveraging AI

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h)

Topics: AI | Cybersecurity

ByteDance’s Seedance 2.0 surpasses Western video models whilst deepfakes threaten societal trust, and AI adoption paradoxically increases worker burnout instead of reducing hours.

● Seedance 2.0 achieves 90% usable output rate with quad-modality input and real-time audio-visual fusion, outperforming Sora and Veo.

● Global AI-enabled fraud losses reached $442 billion in 2025; deepfake-as-a-service platforms cost $20 monthly for sophisticated identity fraud tools.

● Harvard study reveals AI tool users produce 35% more work whilst reporting 22% longer hours, with 62% experiencing burnout versus 38% of minimal users.

“AI was supposed to make my job easier, but now I’m expected to do three people’s work because the tools make it theoretically possible.”

2. Inside ElevenLabs $330M ARR Sales Machine

The Twenty Minute VC

Listen on: Spotify | Apple Podcasts | Podlink (1 h 15 m)

Topics: AI | Startups | Venture Capital

ElevenLabs VP Sales Carles Reina unveils scaling to $330M ARR via ruthless outbound tactics and 20x quotas.

● Set quotas at 20x base salary.

● Land small deals, expand via outbound.

● Prioritise road time over office.

“Salespeople need to be on the road.” - Carles Reina

3. Sequoia CEO coach: Why it’s never been easier to start a company, and never been harder to scale one

Lenny’s Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 15 m)

Topics: Product | Startups | Venture Capital

Sequoia CEO coach Brian Halligan reveals tactics to scale startups amid exploding competition.

● Hire spicy candidates over consensus picks.

● Build teams like 2004 Red Sox mix.

● Apply LOCKS framework to evaluate CEOs.

“Starting a company has never been easier. Scaling one into a durable, high-impact organisation has never been harder.” - Brian Halligan

4. Spinbrush: John Osher. The Electric Toothbrush That Sold for $475M

How I Built This with Guy Raz

Listen on: Spotify | Apple Podcasts | Podlink (1 h 10 m)

Topics: Inventing | Product | Startups

Serial entrepreneur John Osher reveals how he built Spinbrush from spinning lollipops into a $475 million acquisition by Procter & Gamble, becoming the world’s best-selling toothbrush.

● Price products on market demand, not cost: Osher charged $4.99 for 19-cent earrings whilst competitors charging 39 cents sold nothing.

● Scrapped 400,000 defective units to protect brand integrity, then redesigned the toothbrush waterproof within weeks to maintain quality.

● Positioned Spinbrush as acquisition target by licensing Crest name first, making P&G want to buy rather than being pitched to sell.

“Find a way. As an entrepreneur, that is your job. You will come across issues and roadblocks that are different from others.” - John Osher

5. Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company

a16z Podcast

Listen on: Spotify | Apple Podcasts | Podlink (58 m)

Topics: Leadership | Science & Research

Novartis CEO Vasant Narasimhan discusses how he transformed a 250-year-old conglomerate into a focused medicines company, unlocking $180 billion in value whilst advancing breakthrough therapies in cell, gene, and RNA medicines.

● Spun off three public companies and refocused Novartis on four disease areas and three platform technologies: cell and gene therapies, RNA medicines, and radioligand therapies.

● Cell therapies now show extraordinary potential in autoimmune disease, with patients experiencing near-complete disease reversal and functional cures alongside improved manufacturing economics.

● AI is maturing as an enabling technology across R&D, with potential to shorten drug development timelines by two to four years and improve clinical trial success rates.

“The fact that we still treat disease as late as we do, when we know that if you treat earlier, you’re going to win. We have not solved this problem at scale.” - Vasant Narasimhan

• Will Nitze scaled IQ Bar to $125M revenue with just 10 people through lean operations, a hub-and-spoke agency model, and prioritising retail after e-com for massive volume.

• Former Michigan Chief Justice Bridget McCormack champions AI arbitrators in construction disputes, delivering predictable outcomes with human oversight to expand access for businesses.

• Emblem’s Head of Product August Kiles shows how AI cuts private equity due diligence from 100 hours to seconds by indexing data rooms and automating financial models.

• User research expert Caitlin Sullivan demonstrates AI workflows that halve analysis time on surveys and interviews using structured prompts for actionable insights like friction points and competitive gaps.

• HubSpot CTO Dharmesh Shah argues SaaS thrives amid AI by competing with it on low-risk tasks, reusing codebases as training data, and embracing vibe-coding without replacement fears.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. He Built a $125M Brain Food Brand With Just 10 People

The Foundr Podcast with Nathan Chan

Listen on: Spotify | Apple Podcasts | Podlink (50 m)

Topics: Marketing | Product | Startups

Will Nitze scaled IQ Bar to $125M revenue with 10 people using lean operations and retail breakthroughs.

● Avoid bootstrapping in CPG; raise less money more often.

● Run hub-and-spoke model with agencies for scalability.

● Prioritise retail after e-com for maximum volume.

“Bootstrapping is the worst thing you can do in the CPG space.” - Will Nitze

2. The surprising case for AI judges

Decoder with Nilay Patel

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 18 m)

Topics: AI | Startups | Technology

Former Michigan Chief Justice Bridget McCormack unveils AAA’s AI arbitrator for construction disputes, arguing it boosts predictability over flawed humans.

● AI parses claims, verifies party understanding.

● Human arbitrators oversee reasoning and awards.

● Expands access for self-represented businesses.

“If it were more predictable, we would be a more efficient and effective system.” - Bridget McCormack

3. How AI Is Replacing 100-Hour Due Diligence

Built This Week

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (26 m)

Topics: AI | Productivity | Startups | Venture Capital

Emblem’s Head of Product August Kiles reveals AI slashing private equity due diligence from 100 hours to seconds.

● AI indexes data rooms for instant revenue queries.

● Automate reports and financial models in seconds.

● Rule out bad deals faster to boost throughput.

“Private equity due diligence used to take hundreds of hours. Now it takes seconds.” - August Kiles

4. How to Do AI-Powered Discovery

The Growth Podcast

Listen on: Spotify | Apple Podcasts (1 h 13 m)

Topics: AI | Product

User research expert Caitlin Sullivan demos AI workflows halving analysis time without hallucinations.

● Use four prompt elements: context, structure, evidence, actionability.

● Analyse surveys and interviews via multi-step prompting.

● Generate value anchors, friction points, competitive gaps, risk segments.

“it looks like replicating the way that we do rigorous analysis as humans.” - Caitlin Sullivan

5. Is SaaS really dead? Dharmesh Shah from HubSpot on AI, Vibe-Coding & the Future of Work

Agents of Scale

Listen on: Spotify | Apple Podcasts | Podlink (55 m)

Topics: AI | Product | Startups | Vibe Coding

HubSpot CTO Dharmesh Shah reveals why vibe-coding won’t kill SaaS and shares tactics to thrive with AI.

● Compete using AI, not against it.

● Start with low-risk creation tasks.

● Reuse codebases as training data.

“The number of SaaS apps that we have replaced... is exactly zero.” - Dharmesh Shah

• Learn how three founders use OpenClaw agents to automate startups, slashing team needs with bug-hunting Eywa and Meta Ray-Bans integration.

• ERP leader Subhajit Paul shares how AI agents optimise enterprise workflows, mastering order-to-cash and warehouse efficiency with anomaly detection.

• Jonathan Courtney’s framework for turning AI marketing and Claude code into revenue via organic traffic, warm leads, and webinar conversions.

• Siemens CEO Roland Busch discusses how digital twins and industrial AI achieve 95% accuracy, scaling automation across factories despite trade barriers.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. How These 3 Founders are building on Open Claw

This Week in Startups

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (45 m)

Topics: AI | Automation | Product | Startups | Technology

Three founders demo OpenClaw agents automating startups, from support to glasses integration, slashing team needs.

● Eywa agent automates active user lists from email.

● Eywa hunts bugs and suggests fixes via email.

● Sean Liu connects Meta Ray-Bans to OpenClaw for visual context.

“a startup is just a handful of experiments that you’re trying to figure out” - Presh Dineshkumar

2. Subhajit Paul on ERP Automation and AI

Software Engineering Radio

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h)

Topics: AI | Automation | Product | Technology

Subhajit Paul, ERP implementation leader, reveals how AI agents transform enterprise workflows from rigid rules to adaptive decisions.

● Master order-to-cash, procure-to-pay, plan-to-produce flows.

● Optimise warehouses using ML for bin placement efficiency.

● Deploy GenAI agents for anomaly detection and supplier risk.

“ERP is the nervous system of an organisation to run the business.” - Subhajit Paul

3. How I use AI Marketing and Claude Code to make $

The Startup Ideas Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (45 m)

Topics: AI | Marketing | Productivity | Startups | Vibe Coding

Jonathan Courtney reveals how vibe-coded projects turn crickets into revenue using AI-supported promotion.

● Drive traffic via organic posts or paid ads.

● Warm leads in holding patterns like newsletters.

● Convert via webinars and email campaigns.

“Just accept that your role as a CEO is your promoter and don’t be embarrassed about it.” - Jonathan Courtney

5. Siemens CEO Roland Busch’s mission to automate everything

Decoder with Nilay Patel

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 7 m)

Topics: AI | Automation | Leadership | Robotics | Technology

Siemens CEO Roland Busch reveals AI agents and digital twins automating factories amid trade barriers.

● Build physics-based digital twins for products and lines.

● Train industrial AI on proprietary data for 95% hit rates.

● Unbox silos via fabrics for horizontal AI scaling.

“We are the largest automation company. We are automating grids, we’re automating buildings, we’re automating trains, and we are automating manufacturing.” - Roland Busch

• Discover how Reed Hastings, Netflix founder, rejected family culture to build a sports-team performance model that dominated streaming and defeated Blockbuster.

• Learn how Namrta Raghvendra, Meta leader, transformed organisational culture from “move fast and break things” to sustainable innovation with psychological safety embedded.

• Uncover how Lazar Jovanovic, Lovable vibe coder, enables non-coders to ship production AI products by prioritising planning and clarity over traditional coding execution.

• Robby Stein, Google Search VP, reveals AI search evolving into a proactive personal OS that contextualises information and anticipates user needs intelligently.

• Anthropic’s latest AI tools triggered a $300B software stock collapse, exposing agent swarm breakthroughs and intensifying the Anthropic-OpenAI competitive rivalry.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. Netflix: Reed Hastings. “We’re Not a Family.” The Provocative Idea That Helped Build a Streaming Giant

How I Built This with Guy Raz

Listen on: Spotify | Apple Podcasts | Podlink (1 h 29 m)

Topics: Startups | Strategy

Reed Hastings reveals how rejecting family culture propelled Netflix past Blockbuster to streaming dominance.

● Reject family mindset for sports team performance.

● Cut underperformers to maintain talent density.

● Bet big on streaming despite near-failures.

“If you can’t perform at peak, leave.” - Reed Hastings

2. How Meta rebuilt its culture for sustainable innovation

Product Mastery Now for Product Managers, Leaders, and Innovators

Listen on: Spotify | Apple Podcasts | Podlink (32 m)

Topics: Innovation | Leadership | Product | Strategy

Namrta Raghvendra reveals Meta’s shift from ‘move fast and break things’ to enduring innovation culture.

● Replace speed obsession with sustainable practices.

● Embed psychological safety in teams.

● Align incentives to long-term innovation.

“Psychological safety is the foundation for true innovation.” - Namrta Raghvendra

3. Getting paid to vibe code: Inside the new AI-era job

Lenny’s Podcast: Product

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 43 m)

Topics: AI | Product | Productivity | Programming | Startups | Vibe Coding

Lazar Jovanovic (Lovable vibe coder) reveals how non-coders ship production AI products using clarity and judgment.

● Launch parallel prototypes to clarify thinking.

● Spend most time planning, not executing code.

● Use genie-three-wishes model for AI limits.

“I spin up several builds in parallel, a voice brain dump, a refined brief.” - Lazar Jovanovic

4. AI Search as the Personal OS: The Next Interface For Information

Everyday AI Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (32 m)

Topics: AI | Product | Productivity | Technology | UX/UI

Robby Stein, Google Search VP, reveals AI search evolving into proactive personal OS for superior results.

● Opt into Personal Intelligence for context-aware results.

● Use AI Mode for complex, follow-up queries.

● Leverage agentic search for proactive assistance.

“AI search might just be the new personal operating system.” - Robby Stein

5. $300B vanished in 48 hours in a SaaSpocalypse triggered by Anthropic Opus 4.5 and ChatGPT Codex 5.3+Frontier

Leveraging AI

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (58 m)

Topics: AI | Startups | Technology

Anthropic’s AI tools sparked $300B software stock wipeout, igniting OpenAI rivalry amid agent swarm breakthroughs.

● Grasp SaaSpocalypse market crash mechanics.

● Learn about agent swarms.

● Track Anthropic-OpenAI competition escalation.

“$300 billion vanished in 48 hours from software stocks.”

Pick a great podcast fast: Get 5 handpicked, recent podcast episodes in AI, tech, startups, and product—sent 3x weekly.

1. Discover how Jia Li of LiveX AI is deploying real-time 4K holograms to revolutionise fan experiences and bridge digital-physical worlds at major sporting events.

2. Learn how Ben Francis co-founded Gymshark at 19 and leveraged early influencer equity stakes to become the UK’s youngest billionaire through strategic marketing.

3. Uncover how Peter Steinberger uses AI automation to streamline his entire daily routine—from flight bookings to home control—in just 40 minutes.

4. Explore how Substack CEO Chris Best disrupted traditional media by enabling direct creator subscriptions and positioning video as the platform’s next growth frontier.

5. Find out how Mark Gray’s collaborative robot arms utilise AI to enable safe human-robot teamwork and rapid redeployment across industrial applications.

Pick an episode, press play, lace up and get moving.

Podcast Recommendations

1. How AI-Powered Holograms Are Reimagining Fan Experiences at the Big Game

NVIDIA AI Podcast

Listen on: Spotify | Apple Podcasts | Podlink (39 m)

Topics: AI | Technology

Jia Li of LiveX AI unveils real-time 4K holograms transforming Super Bowl fan interactions.

● Deploy real-time 4K holograms for fan engagement.

● Use human-like AI agents for wayfinding.

● Bridge digital-physical worlds at sports events.

“AI reimagines fan experiences with interactive holograms.” - Jia Li

2. Ben Francis: UK’s youngest billionaire

Good Bad Billionaire

Listen on: Spotify | Apple Podcasts | Podlink (45 m)

Topics: Founders | Startups

Gymshark founder Ben Francis shares pizza delivery origins to youngest UK billionaire status via influencer marketing.

● Co-founded Gymshark at 19 in garage.

● Gave influencers equity stakes early.

● Sold 21% stake for $300 million in 2020.

“Bring in people better than you.” - Ben Francis

3. How OpenClaw’s Creator Uses AI to Run His Life in 40 Minutes | Peter Steinberger

Behind the Craft

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (38 m)

Topics: AI | Automation | Productivity | Vibe Coding

OpenClaw creator Peter Steinberger reveals how AI automates flights, home control and daily tasks in just 40 minutes.

● OpenClaw checks flights, adjusts lights, controls bed.

● Default Codex over Opus; handles codebases better.

● Reject plan mode; use ‘let’s discuss’ conversations.

“This will replace 80% of the apps that you have on your phone.” - Peter Steinberger

4. Has Substack Changed Media For Good?

The Prof G Show with Scott Galloway

Listen on: Spotify | YouTube | Apple Podcasts (1 h 6 m)

Topics: Creator Economy | Founders | Product | Startups

Substack CEO Chris Best reveals how his platform disrupted media rivals and eyes video’s rise.

● Substack differentiates via direct creator subscriptions.

● Video integration boosts audience engagement.

● Substack accelerates creator-driven media shift.

“Media’s future favors independent creators.” - Chris Best

5. Collaborative robot arms - Mark Gray

Robot Talk

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (27 m)

Topics: AI | Automation | Hardware | Robotics | Technology

Universal Robots’ Mark Gray reveals how AI-powered cobots enable safe human collaboration and rapid redeployment.

● Teach robots skills via AI.

● Program for visual inspection.

● Demo via city roadshows.

1. Discover how a16z co-founder Marc Andreessen believes demographic collapse can be countered with AI’s productivity boom.

2. Learn from Wix CMO Omer Shai how to build a $100M marketing engine by replacing LTV with Time ROI and balancing brand with performance.

3. Explore host Isar Meitis’s take on AI’s inflection point with Claude Cowork agents, OpenClaw and Kimi 2.5 swarms.

4. Uncover Replit CEO Amjad Masad’s vibe coding revolution that democratises software creation via AI agents and gaming mindsets.

5. Find out from Netlify CEO Matt Biilmann how AI agents explode dev tools to 3 billion users.

Pick an episode below, press play, lace up and get moving.

Podcast Recommendations

1. Marc Andreessen: The real AI boom hasn’t even started yet

Lenny’s Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 45 m)

Topics: AI | Product | Startups | Technology | Venture Capital

a16z co-founder Marc Andreessen explains why AI perfectly counters demographic collapse and unlocks massive productivity gains.

● How to raise kids for an AI world.

● Build E-shaped careers combining skills.

● What will actually happen with AI and jobs.

“The timing has worked out miraculously well. We’re going to have AI and robots precisely when we actually need them.” - Marc Andreessen

2. How Wix Built a $100M Marketing Machine

The Twenty Minute VC

Listen on: Spotify | Apple Podcasts | Podlink (1 h 2 m)

Topics: Marketing | Product | Startups | Strategy | Venture Capital

Wix CMO Omer Shai reveals building $100M marketing engine and ditching LTV for Time ROI metric.

● Replace LTV with Time Return on Investment.

● Balance brand and performance marketing.

● Identify next growth channels early.

“LTV is BS.” - Omer Shai

3. We passed an inflection point, Claude Cowork + OpenClaw + Kimi 2.5 Agent Swarm, Skynet vibes

Leveraging AI

Listen on: Spotify | Apple Podcasts | Podlink (1 h 6 m)

Topics: AI | Automation | Productivity | Startups | Technology

Host Isar Meitis reveals AI’s inflection point with agent swarms, 167K job cuts, and Dario Amodei’s alarm for 2026 business shifts.

● Unpack Claude Cowork agent capabilities.

● Analyse Kimi 2.5 swarm innovations.

●Assess OpenClaw viral network risks.

“The reason I believe we passed an inflection point is because several different technologies that have existed and have evolved have reached a level of maturity that, when combined together, accelerates AI capabilities in an extreme way.” - Isar Meitis

4. Possible: Amjad Masad on vibe coding, AI agents, and the end of boilerplate

Masters of Scale

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (1 h 16 m)

Topics: AI | Founders | Innovation | Product | Programming | Vibe Coding

Replit CEO Amjad Masad explains how AI-powered vibe coding democratises software creation and reshapes who builds.

● Vibe coding emerges as next literacy form beyond syntax mastery.

● Gaming mindsets produce better builders and creative problem-solvers.

● AI agents enable autonomous workflows, not human replacement.

“Vibe coding is the next form of literacy.” - Amjad Masad

5. “Anyone Can Code Now” - Netlify CEO Talks AI Agents

a16z Podcast

Listen on: Spotify | YouTube | Apple Podcasts | Podlink (58 m)

Topics: AI | Product | Programming | Startups | Technology | Vibe Coding

Netlify CEO Matt Biilmann unveils AI exploding dev tools market to 3 billion users via everyday prompting.

● Netlify hits 16,000 daily signups, 5x prior rate.

● 96% new users non-AI coders building React apps.

● 25% users paste errors to LLMs instantly.

“I want to make it my mission to become an equally good developer without writing any code myself.” - Matt Biilmann